Basic Information
VIS ID
TVIS10016140
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
220
Orient
+
Integrated sequence
AGTTACTCTCTTTTTTGCCTTCCGACTTCTTTCCTTCTATTCGAGATCTTCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACA| |TTGTTCACCTCACCATACGGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTAGCCACCTGGGTGGGAAGTAATTTGGAAGATCCAGCA
Host Sequence
Chromosome
chr17
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
22215662/22716335 (Hg38)
End
22215662/22716335 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1180/Upstream/3371761; hsa-mir-10226/Downstream/4577575;
Nearest TSS
ENST00000595228/Upstream/23501; ENST00000583786/Downstream/4283590;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/23653, chr17-CpG: 114/Downstream/4014693
Nearby gene
MTRNR2L1(-191671) ; WSB1(+3405443) ;
Upstream sequence
GGCTCCCACCCTCGATGTGCTCCTGCCTTTGCCTTCTTGCTGGTAACGCTGCCATTGGTGCTGGTAACGCTGCCATTGGTGAAGAACACGGGAGCCCATC
Downstream sequence
aaagcactaggattacaggcatgaagcatcatgctctcgtcaccaactcacatgctgaccatttgactagttcagttattacctgttttactctattagc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate