Basic Information
VIS ID
TVIS10016142
Fusion event
HBV-chr18 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1766
End
1786
Orient
+
Integrated sequence
GCTGGATGTGTCTGCGGCGTT
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
3028821/3028823 (Hg38)
End
3028907/3028909 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-8078/Upstream/2916484; hsa-mir-1-2/Downstream/856444;
Nearest TSS
ENST00000575820/Upstream/15508; ENST00000580139/Downstream/46742;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/15555, chr18-CpG: 20/Downstream/38390
Upstream sequence
AATAAATGCTCAGTAATTTTAAGCACTATGTAGTTATTAAAATTAGCTAATCTAgccaggcgtggtggctcacacctgtaatcccagcactctgggaggg
Downstream sequence
acaaaaatacaaaaattaactaggtgtggtggctcatgcctgtagttccagctactcaggaggctgaggtgggaggattgcttgagcctgggaggcagag
Target sequence
cagcactctgggagggcgatgcgggccgactgctttagcccaggaattcgagaccaacctgggcaaggtggtgagacctcgtctct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate