VISDB Viral Integration Site DataBase

VIS ID

TVIS10016143

Fusion event

HBV-TWSG1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

357

Orient

+

Integrated sequence

CTGTGTTGGGGTGAGTTGATGAATCTAGCCACCTGGGTGGGAAGTAATTTGGAAGATCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATA| |TGGGCCTAAAAATCAGACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGAAGAGAAACTGTTCTCGAATATTTGGTGTCTTTTGGAGTGTGGAT

Chromosome

chr18

Cytoband

p11.22

Reference genome

Start

End

9346022/9346024 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-577 ; hsa-mir-142-3p ; hsa-mir-155-5p ; hsa-mir-4291 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6778-3p ; hsa-mir-149-5p ; hsa-mir-106b-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-545-3p ; hsa-mir-892b ; hsa-mir-3591-3p ; hsa-mir-21-3p

Nearest miRNA

hsa-mir-3976/Upstream/2971599; hsa-mir-1-2/Downstream/1413560;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/10663, chr18-CpG: 105/Downstream/128782

Nearby gene

ANKRD12(-60039) ; RALBP1(+129507) ;

Upstream sequence

TCCCCAGAAGTGATGAAATAAATGCTCAGTAATTTTAAGCACTATGTAGTTATTAAAATTAGCTAATCTAgccaggcgtggtggctcacacctgtaatcc

Downstream sequence

ctttgtgttttacatttttatgggttttgacaaatgcataatgtcttgtatctaccattacagtatcattcagaatagtttcattgctctaaaaatcccc