VISDB Viral Integration Site DataBase

VIS ID

TVIS10016145

Fusion event

HBV-ZNF516 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2817

Orient

+

Integrated sequence

TATCGGGACTGATAATTCTGTCGTGCTCTCCCGCAAGTATACGTCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTT| |GTTTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCCTCCCGGGGCCGCTTGGGGCTCTACCGGCCGCTTCTCCGTCTCCCGTACCGACCGACCACGG

Chromosome

chr18

Cytoband

q23

Reference genome

Start

End

74177432/76465476 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-432-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6739-3p ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-489-3p ; hsa-mir-4256 ; hsa-mir-3913-3p ; hsa-mir-6719-3p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-6730-3p ; hsa-mir-4286 ; hsa-mir-6729-3p ; hsa-mir-2114-5p ; hsa-mir-6873-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-1306-5p ; hsa-mir-4699-3p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-1266-5p ; hsa-mir-1296-3p ; hsa-mir-1908-5p ; hsa-mir-211-3p ; hsa-mir-24-3p ; hsa-mir-3144-5p ; hsa-mir-3179 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3191-3p ; hsa-mir-3196 ; hsa-mir-3202 ; hsa-mir-3612 ; hsa-mir-3934-3p ; hsa-mir-4270 ; hsa-mir-4284 ; hsa-mir-4441 ; hsa-mir-4481 ; hsa-mir-4518 ; hsa-mir-4652-5p ; hsa-mir-4706 ; hsa-mir-4745-5p ; hsa-mir-4747-5p ; hsa-mir-4749-5p ; hsa-mir-491-5p ; hsa-mir-5196-5p ; hsa-mir-524-3p ; hsa-mir-525-3p ; hsa-mir-650 ; hsa-mir-663a ; hsa-mir-6754-5p ; hsa-mir-6777-5p ; hsa-mir-6787-5p ; hsa-mir-6797-5p ; hsa-mir-6810-5p ; hsa-mir-6816-5p ; hsa-mir-6825-5p ; hsa-mir-6889-5p ; hsa-mir-9500

Nearest miRNA

hsa-mir-1-2/Upstream/3612094;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/6641, chr18-CpG: 396/Downstream/25318

Nearby gene

SMIM21(-1037843) ; LINC00908(+63179) ;

Upstream sequence

GTGATTGATCATGCATGATTGAGTTTTGTCTATTAAAGCAATTGATAAGTTACTAAAATGGCACCAAAAGAAATTAGAAAAAAATTGTTGCAAATGTCAG

Downstream sequence

GACAGCACACGGGAGAAATGCTCCAGGATGGAGGGACAGACAGGGAAGAAACTTTATACCTTTACTTTCAGATGTATTAACCAGTAACAGACAAAGGCAG