Basic Information
VIS ID
TVIS10016146
Fusion event
HBV-chr19 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1047
Orient
-
Integrated sequence
GGGTATCTTATATAAAAGAGAGACGACACGTAGCGCCTCATTTTGCGGGTCACCATATTCTTGGGAACAAGAGCTACAGCATGGGAGGTTGGTCTTCCAA| |ACCTCGAAAAGGCATGGGGACAAATCTTTCTGTCCCCAATCCACTGGGATTCTTCCCCGATCATCAGTTGGACCCTGCATTCAAAGCCAACTCAGAAAAT
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14946842/14836030 (Hg38)
End
14946842/14836030 (Hg38)
Orient
-
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/306390; hsa-let-7e/Downstream/343253;
Nearest TSS
ENST00000633603/Upstream/654; ENST00000248072/Downstream/5847;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/263848, chr19-CpG: 92/Downstream/143174
Nearby gene
OR7A5(-7566) ; OR7A10(+4917) ;
Upstream sequence
ATGGATTTTGTCTGCCTTCCTCTCCACCCCCAGAGCTCTGtcacacaacatggctttattgaacacttgcacgcctggtcttcgtctagatattagggat
Downstream sequence
TTTAATGCTTGTCAGACAAATTAAGAACTGTCTTTTAGTTCTTCATTGATAAAATGTGTACCAATTACAAGAGATATATTTAGACCCTTTTATGCAcatt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate