CTNNA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016151
Fusion event
HBV-CTNNA2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1800
End
1822
Orient
-
Integrated sequence
CTGCATCCTGCTGCTATGCCTCA
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
80251951/80024825 (Hg38)
End
80252049/80024923 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
CTNNA2
Nearest miRNA
hsa-mir-1285-2/Upstream/158242; hsa-mir-10b/Downstream/5758677;
Nearest TSS
ENST00000437798/Upstream/326979; ENST00000493024/Downstream/5628;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/511708, chr2-CpG: 101/Downstream/277629
Nearest cancer related gene
CTNNA2(TSG, No orient, 0)
Upstream sequence
TCTGGTGCTGCAAGGTATTACACTTCTGAAAGATGAAATTACATTTGTTACAGTGGAAAGGCAGCTGAATGGTTTAGTCTAGTTTCATCTCTCTGTCAAA
Downstream sequence
aggaagattttgttgagcagtggaagtgggtctcagagggaaggggagctggaaggggcaaggcagtgggaagataatcttcccctcgagttcgaccatc
Target sequence
acagccttttattttacactctgtcacttggtacctgagttcttgtctggtgtccaggaagaattaggtcatgcaaatgaattgaaagatggtgtatg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate