Basic Information
VIS ID
TVIS10016157
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1917
Orient
-
Integrated sequence
GCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCATCAACCACCAGCACCGGACCATGCAGAAC| |CTGCACGACTCCTGCTCAAGGAACCTCTATGTTTCCCTCATGTTGCTGTACAAAACCTATGGACGGAAACTGCACATGTATTCCCATCCCATCATCTTGG
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
11601261/11620613 (Hg38)
End
11601261/11620613 (Hg38)
Orient
+
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/970918; hsa-mir-1-1/Downstream/6850002;
Nearest TSS
ENST00000382410/Upstream/78966; ENST00000450368/Downstream/66710;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/945650, chr20-CpG: 37/Downstream/66261
Nearby gene
JAG1(-946567) ; BTBD3(+270215) ;
Upstream sequence
cccaatgacccctggttcctggtgttcatgccctcgtgttgtcccctcccatgctgaagaatgctagtctatataaccaattagatattgcagacattat
Downstream sequence
CTACTCTGGTGCAGAGTCATGCAGAAACAAAATGCCGTCAGTACCTTTGCCTGATGAGAACAGGGAGCATGCAACGGCCTTTATCCAACATTTGATCAAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate