Basic Information
VIS ID
TVIS10016158
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
162
Orient
-
Integrated sequence
CTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCCGACTTCTTTCCTTCTATTC| |GAGATCTTCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACGGCACTCAGGCAAGCTATTCTGTG
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
44554233/45925594 (Hg38)
End
44554233/45925594 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-103a-2/Upstream/220414; hsa-mir-1-1/Downstream/1241373;
Nearest TSS
ENST00000382410/Upstream/13439; ENST00000616084/Downstream/9034;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/13276, chr20-CpG: 92/Downstream/8659
Nearby gene
PLTP(-13447) ; PCIF1(+9083) ;
Upstream sequence
CATTGAGTTACTTCTTTAGTTTTGATGCTAGAATGCTTAGAACTAAGTATTTTGCACAAATCTCCTTAATGACATCGTGGGTTTTAATCTCTTAATGGGT
Downstream sequence
GGAGGGAATAGTACACCACATCAGACGCTTCCAAGGCCAGGAAGACCAAGGGAGACGCCCCCATTCCTCTCATCTATTCTTGGCCTAAATGGCTTCTCTC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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