VISDB Viral Integration Site DataBase

VIS ID

TVIS10016161

Fusion event

HBV-SIM2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

3133

Orient

-

Integrated sequence

TGCCCAAGGTCTTACAGGAGAGGACTCTTGGACTTTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTGTGTTTGCTGAGTGGGAGGA| |GTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTATTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC

Chromosome

chr21

Cytoband

q22.13

Reference genome

Start

End

38107174/36734873 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-7641 ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4762-5p

Nearest miRNA

hsa-let-7c/Upstream/1014065; hsa-mir-3197/Downstream/2712137;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/25340, chr21-CpG: 132/Downstream/12619

Nearby gene

CLDN14(-158307) ; HLCS(+16014) ;

Upstream sequence

GAGTCGGGGTCTTCATGGTATGGAGCTTTGTGATTGTGGAGGCCTCACTCTCCTTCCCAGGTACAGAACCTGGGCCAGAGGGGCCAACCCCAGGCCTCCT

Downstream sequence

GTTCCTGCCTCTCCATCCCCAGGGCTGGGTGGCACCTGTTTGATTTCCTGAAActccagaagctgccccagagcctggagttgaagtgcaatggttgatt