Basic Information
VIS ID
TVIS10016162
Fusion event
HBV-chr22 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
20
Orient
+
Integrated sequence
TTTTTCACCTCTGCCTAATC| |ATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGG
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
19548532/19561009 (Hg38)
End
19548532/19561009 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-3198-1/Upstream/1580048; hsa-let-7a-3/Downstream/402744;
Nearest TSS
ENST00000624155/Upstream/33464; ENST00000452326/Downstream/5830;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/36278, chr22-CpG: 30/Downstream/5482
Nearby gene
CLDN5(-35672) ; LINC00895(+5120) ;
Upstream sequence
cacctataccccataaattcatacaaataaaaaaGAAATTTAGGTGATAAGAGCTATGGGCCTTGGTTACCAGTTCTGTGCATGTGCATGAGTGTGTGAC
Downstream sequence
TTGTGGCATCACACGGTGTCAGGGAGCCGATCGGGGCACTgggagaggtgataaactagaatttggaaatgctgaattcgaggtgcctgtgaggtagcaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate