Basic Information
VIS ID
TVIS10016167
Fusion event
HBV-chr3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1179
Orient
-
Integrated sequence
TCCCCAATCCACTGGGATTCTTCCCCGATCATCAGTTGGACCCTGCATTCAAAGCCAACTCAGAAAATCCAGATTGGGACCTCAATCCATACAAGGACAA| |CTGGCCGGATGCCAACAAGGTGGGAGTGGGAGCATTCGGGCCAGGGTTCACCCCTCCCCATGGGGGCCTGTTGGGGTGGAGCCCTCAGGCTCAGGGCATA
Host Sequence
Chromosome
chr3
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
116581304/116862457 (Hg38)
End
116581304/116862457 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7g/Upstream/12090; hsa-mir-12124/Downstream/3222107;
Nearest TSS
ENST00000440867/Upstream/152488; ENST00000487512/Downstream/58974;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1077723, chr3-CpG: 75/Downstream/1134260
Nearby gene
TUSC7(-145417) ; IGSF11(+2038174) ;
Nearest cancer related gene
TUSC7(TSG, -145417) ;
Upstream sequence
ctcccttccctgtggagtgtactttcaataaatttcggcttttgttgcttcattctctttgctttgtttgtaaattttgtccaattctttgttcaaaatg
Downstream sequence
TGCAAAAAGGTAGAGACCCCTGATACATATCTTAACCTGTATCATCATGTCAGTACCTTCCTAAATCCTCAAACTTGTGGTTGCCTTGGAAATGTGGCAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate