Basic Information
VIS ID
TVIS10016168
Fusion event
HBV-LOC107986022 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
371
Orient
+
Integrated sequence
GTTGATGAATCTAGCCACCTGGGTGGGAAGTAATTTGGAAGATCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATATGGGCCTAAAAATC| |AGACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGAAGAGAAACTGTTCTCGAATATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCTG
Host Sequence
Chromosome
chr3
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
117661703/117942856 (Hg38)
End
117661703/117942856 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986022
Nearest miRNA
hsa-let-7g/Upstream/1092489; hsa-mir-12124/Downstream/2141708;
Nearest TSS
ENST00000440867/Upstream/152183; ENST00000477009/Downstream/54736;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/2158122, chr3-CpG: 75/Downstream/53861
Nearby gene
TUSC7(-1225816) ; IGSF11(+957775) ;
Upstream sequence
CTTGAAGCATAAATAAGCCTTAGGTAGGTGGAGGAAAGATATAAGGATAGGGAAGATACTTTGAGCAAGGGAGCAAAGTATGAGTATCACTGTTGGAGAG
Downstream sequence
aagggcaattctgatgcaggcttagaagaagaagaagaagagatctaaggagaaagcttcaatcttctaagggattacctaagtggtcatgaacagattg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate