Basic Information
VIS ID
TVIS10016172
Fusion event
HBV-chr3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1268
Orient
+
Integrated sequence
TACAAGGACAACTGGCCGGATGCCAACAAGGTGGGAGTGGGAGCATTCGGGCCAGGGTTCACCCCTCCCCATGGGGGCCTGTTGGGGTGGAGCCCTCAGG| |CTCAGGGCATACTCACAACTGTGCCAGCAGCACCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGGCAGCCTACTCCCTTATCTCCACCTCTAAGGGA
Host Sequence
Chromosome
chr3
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
152577625/152859836 (Hg38)
End
152577625/152859836 (Hg38)
Orient
-
Fragile sites / regions
FRA3D
Nearest miRNA
hsa-let-7g/Upstream/1293841; hsa-mir-1224/Downstream/6422810;
Nearest TSS
ENST00000440867/Upstream/25143; ENST00000323534/Downstream/301939;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/23913, chr3-CpG: 228/Downstream/300643
Nearby gene
P2RY1(-21782) ; RAP2B(+302403) ;
Upstream sequence
agtaaaggccagaaatattgctaaacgtcctataatgcaaaggacagcacccctcccacctcctcaagacaagtaattatccagcccaaattgtgaatgg
Downstream sequence
taggatttattgaatgtgcaggggatgagggagaagtctaggcctcacaacttccaaatgtcttgcttgaacaataaatggggtgaatttcaaggccatt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate