Basic Information
VIS ID
TVIS10016177
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1787
Orient
-
Integrated sequence
GTGTGTCTTGGCCAAAATTCGCAGTCCCAAATCTCCAGTCACTCACCAACTTGTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTT| |TTATCATCTTCCTCTGCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATC
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64905157/64039439 (Hg38)
End
64905157/64039439 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/3116755; hsa-mir-1243/Downstream/2237385;
Nearest TSS
ENST00000502981/Upstream/545161; ENST00000509473/Downstream/242097;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/689573, chr4-CpG: 32/Downstream/1630036
Nearby gene
LPHN3(-1966989) ; TECRL(+239019) ;
Upstream sequence
TCTGTTTTATCTACTATGTTAGACAGTTTCTTGCCTTGCTGAAAACACATGACTTCTTTTTTTCAGGCTATTAGTTCGTTACACCAAGAAAGTACCCCAA
Downstream sequence
actcggtctcaaaaaaaaaaaacaaaaTCTTCCATTAGGTGTTCCACCAGAAGCTTACAGAGGCAGTGACACAGAACACATTATATAGAGTTAGCTTTGG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate