Basic Information
VIS ID
TVIS10016179
Fusion event
HBV-chr5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1765
Orient
-
Integrated sequence
CAATTTTCTAGGGGGAACACCCGTGTGTCTTGGCCAAAATTCGCAGTCCCAAATCTCCAGTCACTCACCAACTTGTTGTCCTCCAATTTGTCCTGGTTAT| |CGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTGCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCG
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
21321786/21321677 (Hg38)
End
21321786/21321677 (Hg38)
Orient
+
Fragile sites / regions
FRA5E
Nearest miRNA
hsa-mir-10397/Upstream/4165685; hsa-mir-103a-1/Downstream/10614425;
Nearest TSS
ENST00000502646/Upstream/705272; ENST00000606105/Downstream/19698;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1015850, chr5-CpG: 38/Downstream/137683
Nearby gene
CDH18(-1333433) ; GUSBP1(+137802) ;
Upstream sequence
TCTGGGTGCTCTAAGCCAAGGGGCTTTCCTTTCCCCAGGCTTCACAGCGAGTGAGCTGCAGAGATGAGAGCCACGCCCAGCTACTCCATCCGCACCCAGC
Downstream sequence
gaagaaaaggcaagaaaaaacaagaCAGACAAAACATTGGAAAAATATGACAGAGAGAGTAAGAATTGtatatatcataattttaaaatattttaaattt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate