Basic Information
VIS ID
TVIS10016181
Fusion event
HBV-LOC107986433 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
705
Orient
-
Integrated sequence
TCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGAAACTTTACGGGGCTTTATTCTTCTACTGTACCTAACTTTAATCCTGAT| |TGGCAAACTCCTTCTTTTCCTGACATTCATTTGCAGGAGGACATTGCTGATAGGTGTAAGCAATTTGTGGGACCCCTAACAGTAAATGAAAACAGGAGAT
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
90553996/91258179 (Hg38)
End
90553996/91258179 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986433
Nearest miRNA
hsa-mir-10397/Upstream/1241459; hsa-mir-103a-1/Downstream/2362517;
Nearest TSS
ENST00000502646/Upstream/31108; ENST00000484429/Downstream/22963;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/699040, chr5-CpG: 36/Downstream/22351
Nearby gene
ADGRV1(-93963) ; ARRDC3(+110544) ;
Upstream sequence
TTTTCCCCTTCCTTCTGATACAATATTCTGCAACCAGGTCTCCCTGAGGCTGACTCATTTTTTTTTTTTTTTTCACATATCTGCTCAATTACACCTTTTC
Downstream sequence
TATAATTGTCATTTTATGTGCTCAACATCATAGAAGTAAAAATTAGTCTCCAAACAAGCTTTGTTCAAATGTGTTTGCAAATGTTCTTTCTGTGTGCATT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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