Basic Information
VIS ID
TVIS10016183
Fusion event
HBV-LOC102724458 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
823
Orient
-
Integrated sequence
CCTGACATTCATTTGCAGGAGGACATTGCTGATAGGTGTAAGCAATTTGTGGGACCCCTAACAGTAAATGAAAACAGGAGATTAAAATTAATTATGCCTG| |CTAGATTTTATCCCAATGTTACCAAATACTTGCCCTTAGATAAAGGAATTAAACCCTATTATCCAGAGCATGTAGTTAATCATTACTTCCAGACGAGACA
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
163144289/163717283 (Hg38)
End
163144289/163717283 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC102724458
Nearest miRNA
hsa-mir-10397/Upstream/3231833; hsa-mir-103a-1/Downstream/4448562;
Nearest TSS
ENST00000502646/Upstream/200066; ENST00000522426/Downstream/492348;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/211343, chr5-CpG: 17/Downstream/3261196
Nearby gene
MAT2B(-197961) ; TENM2(+3567553) ;
Upstream sequence
CTATTTTTGGTTCTTCTTGTGGGTACTTAGTTATTACTCTGCATCTTGAAAGGTGAAAACTAGAACCAAAGTGAACCATGTGATTTTGAGCGTCTTAATG
Downstream sequence
TCTGTCTCATGCAGTTCTTGAAGCAAATATGAGAAATTATACTTTTTAAATCCTTTAAATAGTTAAAATGTACAAAGATTCATATTTAATGTTACTTACA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate