Basic Information
VIS ID
TVIS10016186
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
2970
Orient
-
Integrated sequence
GGGGCTCTACCGGCCGCTTCTCCGTCTCCCGTACCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGAC| |CGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACTGGAACCTGCCCAAGGTCTTACAGGAGAGGACTCTTGGACTTTC
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
84964838/84255120 (Hg38)
End
84964838/84255120 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/5715811; hsa-mir-1202/Downstream/6057622;
Nearest TSS
ENST00000381078/Upstream/27485; ENST00000591225/Downstream/215784;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/27110, chr6-CpG: 129/Downstream/507864
Nearby gene
CEP162(-27503) ; TBX18(+479318) ;
Upstream sequence
GTGAAGCAGTGTTAATGAagagtttttattttttaattcttacatgtctggcaacgtaccaggcggtttgcatactttatttggctcaatcattgcaact
Downstream sequence
TGCAGGGGATATCCAAACTATCAGTATCCAGCCAAAAGTGCCCTGATACACATGGAATACAGCTTAAAGACCACTGGCCgtagcggaaagaacaacgtct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate