Basic Information
VIS ID
TVIS10016187
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
2103
Orient
+
Integrated sequence
TCCCATCATCTTGGGCTTTCGCAAAATACCTATGGGAGTGGGCCTCAGTCCGTTTCTCATGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGG| |GCTTTCCCCCACTGTCTGGCTTTCAGTTATAGTGATGATATGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTATACCGCTGTTACCAATT
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
110196312/109875109 (Hg38)
End
110196312/109875109 (Hg38)
Orient
-
Fragile sites / regions
FRA6F
Nearest miRNA
hsa-mir-10398/Upstream/3090889; hsa-mir-1202/Downstream/9193938;
Nearest TSS
ENST00000381078/Upstream/48587; ENST00000275169/Downstream/103147;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/183543, chr6-CpG: 143/Downstream/103053
Nearby gene
FIG4(-49678) ; GPR6(+103985) ;
Upstream sequence
ggaaacaacaaacactgggatctacttgagggtgggcttcgtacttgggtgatgaaataatatgtacaacactctcctgtgacacattgtttacctatgt
Downstream sequence
AAGGTGGAAAAAACCCCCACACTATACATTTTGTTCCATTGCTTTTCCTAGCTCAGTCAGGAGACCTTTCTTATTAGATTCACTCACTTTGTAACTAATA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate