Basic Information
VIS ID
TVIS10016188
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
734
Orient
-
Integrated sequence
TTCCTTGGACTCATAAGGTGGGAAACTTTACGGGGCTTTATTCTTCTACTGTACCTAACTTTAATCCTGATTGGCAAACTCCTTCTTTTCCTGACATTCA| |TTTGCAGGAGGACATTGCTGATAGGTGTAAGCAATTTGTGGGACCCCTAACAGTAAATGAAAACAGGAGATTAAAATTAATTATGCCTGCTAGATTTTAT
Host Sequence
Chromosome
chr6
Cytoband
q27
Reference genome
GRCh37/hg19
Start
165006651/164585618 (Hg38)
End
165006651/164585618 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10398/Upstream/5820865; hsa-mir-1913/Downstream/1923736;
Nearest TSS
ENST00000381078/Upstream/236974; ENST00000456118/Downstream/242132;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/248271, chr6-CpG: 31/Downstream/748656
Nearby gene
QKI(-1007023) ; C6orf118(+686501) ;
Upstream sequence
tgcagtgaattgagatcgagccactgcactcccagcttgggtgacagagcgagattccgtctcagaaaaaaaaaaaaaaaaaaaggaaaaTCTTTGCCCC
Downstream sequence
tggggaaagcaagaagaatggaacccagagcaaaaaatagagttgtttgacgtgcacatgagcagttcatccatttcaacaggaacgaaagcagagctgc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate