Basic Information
VIS ID
TVIS10016189
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
538
Orient
+
Integrated sequence
TGTCTTTTGGAGTGTGGATTCGCACTCCTCCTGCATATAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGG| |CAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCACCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCC
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
57904573/57844867 (Hg38)
End
57904573/57844867 (Hg38)
Orient
+
Fragile sites / regions
FRA7A
Nearest miRNA
hsa-mir-1183/Upstream/439777; hsa-mir-10399/Downstream/5776223;
Nearest TSS
ENST00000635602/Upstream/394690; ENST00000418297/Downstream/5209564;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/9042, chr7-CpG: 153/Downstream/23209
Nearby gene
ZNF716(-371308) ; ZNF733P(+4847096) ;
Upstream sequence
cccggcctgttatgtgatttttgatgcaagaaaattttttttccatcccagtgttctaagagaatctcctatgttttcttctttaacccgtcgaaagtcc
Downstream sequence
ctaaggtcaggaatttgagaccagtctgggtaacatagtgagaccctgtatctaCAAaaaataaaataaaataaaataaaataaaGGAAAAGTGAAGGAG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate