ATP6V0A4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016192
Fusion event
HBV-ATP6V0A4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
518
Orient
-
Integrated sequence
AACTGTTCTCGAATATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCTGCATATAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACT| |ACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCACCGCGTCGCAGAAGATCTCAATCTCGGG
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
End
138471957/138787212 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/663391; hsa-mir-10399/Downstream/256888;
Nearby gene
ATP6V0A4(-13175) ; TMEM213(+10781) ;
Upstream sequence
tgcagtgtgccgagatcgtgtaattgcactccagcctgggccacagaTTCAAAATCAAAGCTTTTTAGATTCCCTGTACTATGAGTCTAGTGGTTCTTTC
Downstream sequence
GTGTTAGGAAGTATACATAGCAAAACCCTTTCTGGGCATCACGTATCCCCTCTGCAGAGTCCTGCGGACCCCAGAGAAAATTCTCCCCACAAAGGATGGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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