Basic Information
VIS ID
TVIS10016193
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1773
Orient
-
Integrated sequence
TAGGGGGAACACCCGTGTGTCTTGGCCAAAATTCGCAGTCCCAAATCTCCAGTCACTCACCAACTTGTTGTCCTCCAATTTGTCCTGGTTATCGCTGGAT| |GTGTCTGCGGCGTTTTATCATCTTCCTCTGCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCT
Host Sequence
Chromosome
chr8
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
47795569/46883947 (Hg38)
End
47795569/46883947 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-124-1/Upstream/3987672; hsa-mir-10400/Downstream/14830841;
Nearest TSS
ENST00000518652/Upstream/43052; ENST00000524012/Downstream/38614;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/266195, chr8-CpG: 32/Downstream/70800
Nearby gene
LINC00293(-28162) ; LOC100287846(+305360) ;
Upstream sequence
ACTGATTTTTTTTTTAAGGAAATACTCATTAACAAAAAAATGTGCAGGTACGGGAGGGACAATAGTGAGATTCTCAAGTTATTTTTTTCTTTCCATTTTT
Downstream sequence
ctgcaatttgtattaatcccatctcttggcagagtctagaatatgaaggagagtcacatcacctaggttttgcaatcagtggtaggccacaatttgtttg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate