Basic Information
VIS ID
TVIS10016195
Fusion event
HBV-LOC107986891 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1337
Orient
-
Integrated sequence
CATGGGGGCCTGTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTCACAACTGTGCCAGCAGCACCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGGC| |AGCCTACTCCCTTATCTCCACCTCTAAGGGACACTCATCCTCAGGCCATGCAGTGGAACTCCACCACTTTCCATCAAACTCTTCAAGATCCCAGAGTCAG
Host Sequence
Chromosome
chr8
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
74082529/73170294 (Hg38)
End
74082529/73170294 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986891
Nearest miRNA
hsa-mir-124-1/Upstream/8791037; hsa-mir-10400/Downstream/1378249;
Nearest TSS
ENST00000518652/Upstream/46206; ENST00000518870/Downstream/89208;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/76673, chr8-CpG: 33/Downstream/115324
Nearby gene
SBSPON(-77022) ; C8orf89(+71034) ;
Upstream sequence
TCAAATAGTATCTCTTCCCTTCTAATAATGCCACCCCTACTTTCTCCTTACAGAGCAATTTCATGTGAGTTTTAAGAGAACAGCCTGTTGTCTGAACTAA
Downstream sequence
ctacttctatagatcaatttctgatacagtgctagcacagagttagcactcaagaaatatttgatgaatgaatgaacgaatgaatgaCTAATGGTGGCAG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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