Basic Information
VIS ID
TVIS10016196
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1563
Orient
+
Integrated sequence
CCAGTTCAGGAACAGTAAGCCCTGCTCAGAATACTGCCTCTGCCATATCGTCAACCTTCTCGAAGACTGGGGACCCTGTACCGAACATGGAGAACATCGC| |ATCAGGACTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAAAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCT
Host Sequence
Chromosome
chr8
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
115564013/114551784 (Hg38)
End
115564013/114551784 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-12123/Upstream/1908201; hsa-mir-10400/Downstream/2322944;
Nearest TSS
ENST00000518652/Upstream/269648; ENST00000415088/Downstream/940437;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1118928, chr8-CpG: 33/Downstream/1096421
Nearby gene
CSMD3(-1114771) ; TRPS1(+856710) ;
Upstream sequence
tactccctctgcctagaaccctttgcctgtatgtgattattctttcttatcactcaggtatcaactcagataacatctcctttaagatggagtctgaaca
Downstream sequence
GGGTCAGGGTAAAAAATAGAATGAGCATTTTCATATGCCAGATATATCCCCAAAATAATTCACTGGTCATTTGGAGAGGGAACAGATTCATATATGGACT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate