hsa-mir-3199 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016197
Fusion event
HBV-TONSL integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
724
Orient
+
Integrated sequence
AATGTTAGTATTCCTTGGACTCATAAGGTGGGAAACTTTACGGGGCTTTATTCTTCTACTGTACCTAACTTTAATCCTGATTGGCAAACTCCTTCTTTTC| |CTGACATTCATTTGCAGGAGGACATTGCTGATAGGTGTAAGCAATTTGTGGGACCCCTAACAGTAAATGAAAACAGGAGATTAAAATTAATTATGCCTGC
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145667697/144442314 (Hg38)
End
145667697/144442314 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
TONSL
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-92a-3p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6747-3p ; hsa-mir-4722-3p ; hsa-mir-6727-3p ; hsa-mir-1203
Nearest miRNA
hsa-mir-1204/Upstream/6695; hsa-mir-10400/Downstream/20171;
Nearest TSS
ENST00000518652/Upstream/4639; ENST00000525461/Downstream/542;
Nearest CpG islands
chr8-CpG: 18/Target, None/Upstream, None/Downstream
Nearby gene
VPS28(-13770) ; CYHR1(+7617) ;
Upstream sequence
gaatcatttaacttttctttttcttttgtttctcccacctgtaaaatggggctaatgatgatgcatatcttatagggttataagaatagtaaaatgaggt
Downstream sequence
CCAAGCAGCGCATAGCCTGGGAGTGCTGGCCCGCGCGCCAGTGGATGGTGCCCAGGTTGTAGCGGGCGCGGAATAGGTCCTCGTAAAGGTGGTTCTGCCT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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