Basic Information
VIS ID
TVIS10016198
Fusion event
HBV-chr9 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1306
Orient
-
Integrated sequence
GGGAGCATTCGGGCCAGGGTTCACCCCTCCCCATGGGGGCCTGTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTCACAACTGTGCCAGCAGCACCTCCT| |CCTGCCTCCACCAATCGGCAGTCAGGAAGGCAGCCTACTCCCTTATCTCCACCTCTAAGGGACACTCATCCTCAGGCCATGCAGTGGAACTCCACCACTT
Host Sequence
Chromosome
chr9
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
88144000/85529085 (Hg38)
End
88144000/85529085 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-101-2/Upstream/1559228; hsa-let-7a-1/Downstream/3216751;
Nearest TSS
ENST00000422679/Upstream/858425; ENST00000416045/Downstream/49940;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/6015, chr9-CpG: 127/Downstream/212140
Nearby gene
NTRK2(-505495) ; KRT8P41(+17453) ;
Upstream sequence
TCGTTATCATTGTTACTACTATCATTGTTGATATTATTTTATAACAGTGCTAAGTGACACCTTGAGCCAACGCCAAGCTGTTCGCTATCTAAATATAGAA
Downstream sequence
tcactcatgtggctacaggaaggcctcagacagtttgtttctgatttcatgcacatgggcctccatccagggctgcctcactacatggcaattggcttct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate