Basic Information
VIS ID
TVIS10016199
Fusion event
HBV-chrX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
2966
Orient
-
Integrated sequence
GCTTGGGGCTCTACCGGCCGCTTCTCCGTCTCCCGTACCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCC| |GGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACTGGAACCTGCCCAAGGTCTTACAGGAGAGGACTCTTGGAC
Host Sequence
Chromosome
chrX
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
128662871/129528894 (Hg38)
End
128662871/129528894 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7f-2/Upstream/8157841; hsa-mir-105-1/Downstream/4640484;
Nearest TSS
ENST00000429181/Upstream/5394; ENST00000486673/Downstream/10955;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/5465, chrX-CpG: 43/Downstream/11262
Nearby gene
SMARCA1(-5411) ; OCRL(+11380) ;
Upstream sequence
AATCtctgacactattacatattttacatattatttttagtgtgtctctgactcattaaaatgtaaacctgatgaaaatagagatttttgtctgttctgt
Downstream sequence
ctctctcctctgatttgcatctgtaaaatgggtataataatacctaattcaacgtgatctcatgaggatttaatgtaaaatatgtgtataaaacatttaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate