Basic Information
VIS ID
TVIS10016207
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
402
End
437
Orient
+
Integrated sequence
TTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTG
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
186442423/186473291 (Hg38)
End
186442458/186473326 (Hg38)
Orient
-
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/6034901; hsa-mir-1182/Downstream/6243002;
Nearest TSS
ENST00000473358/Upstream/12169; ENST00000609032/Downstream/48447;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/97575, chr1-CpG: 23/Downstream/207353
Nearby gene
LOC102724919(-3000) ;
Upstream sequence
AGTGTGCTAGGGAATAAAAGGGAATAACTGCCCTTATTCACTAAACTTCTCAGCAGGAACTCAAATTAAGTACGGGATAGGAAAGAGTAGGCAGCAAAAA
Downstream sequence
ACCCCAGCCAAGAGTGACCAAACTTAGGAAAACAAATACATTTGATGTTTAAAAATATCTAAACTCAGTGAATTAAGAAAGCATTTGCTTGGAAATGATT
Target sequence
AAAACGTTAAATAAGGAAATAGACATTTATTTTTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate