Fusion event
HBV-CR1L integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
TGCGCACCAGCACCATGCAACTT
End
207868524/207695179 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/1220244; hsa-mir-1182/Downstream/106673;
Upstream sequence
GAGAGTCATGGGATCCCAGTTCGTGTTGGACAGGACATTAGAGAAGATCCAGTCTTATCATTCTACTTGTGTATGAAAACTATTCTCTTCTCAGTAACAT
Downstream sequence
cagaggtgagatcatggcttactgcaaccgccacctccctggctcaagcaattctcctgcctgagcctcccaagcagctgggactacaggtgcatgctac
Target sequence
ccagtttttctaggtttgtctgttttgttttgcttgagacagggtcttgatctgtcactcaagttggactg
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.