Basic Information
VIS ID
TVIS10016210
Fusion event
HBV-LOC101927711 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2951
End
2986
Orient
+
Integrated sequence
AATCCCAACAAGGACACCTGGCCAGACGCCAACAAG
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
232979289/232843543 (Hg38)
End
232979324/232843578 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
LOC101927711
Nearest miRNA
hsa-mir-101-1/Upstream/1823619; hsa-mir-1537/Downstream/780574;
Nearest TSS
ENST00000473358/Upstream/38651; ENST00000479125/Downstream/107027;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/37582, chr1-CpG: 40/Downstream/106867
Upstream sequence
GCCCTTTGGTTGCCAGACCTGGATATAAGAGCACAGGCAGATAGGTAGCTATAACCACCAGCACATTCTCCCTTTTGGCCCCCTCTCCATATCACACCCA
Downstream sequence
TTGGTAGAAAAGGCTAGCTAGATCCAAACACTGACAAAGAAAAAGAAGCTTGGATGGAGAGAGTAGATCTCGCTCAGAGGATCTTGATAGATTAGAAGCA
Target sequence
TCCGAATTAACATAGCACACAGAGAGATATTCAGG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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