VISDB Viral Integration Site DataBase

VIS ID

TVIS10016212

Fusion event

HBV-TOMM20 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

2441

End

2476

Orient

+

Integrated sequence

ATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGG

Chromosome

chr1

Cytoband

q42.3

Reference genome

Start

End

235274633/235111318 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-221-3p ; hsa-let-7d-5p ; hsa-mir-93-3p ; hsa-mir-503-5p ; hsa-mir-331-3p ; hsa-mir-20a-5p ; hsa-mir-502-5p ; hsa-mir-1233-5p ; hsa-mir-6778-5p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548z ; hsa-mir-548ac ; hsa-mir-548bb-3p ; hsa-mir-876-5p ; hsa-mir-1290 ; hsa-mir-3167 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-7150 ; hsa-mir-1273h-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-1193 ; hsa-mir-6894-5p ; hsa-mir-3665 ; hsa-mir-3605-5p ; hsa-mir-2392 ; hsa-mir-5197-5p ; hsa-mir-670-3p ; hsa-mir-8056 ; hsa-mir-3165 ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-3658 ; hsa-mir-3653-3p ; hsa-mir-5186 ; hsa-mir-5197-3p ; hsa-mir-4523 ; hsa-mir-580-5p ; hsa-mir-224-5p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-580-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-4433a-5p ; hsa-mir-668-3p ; hsa-mir-1224-3p ; hsa-mir-628-5p ; hsa-mir-4303 ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-3124-3p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-1915-5p ; hsa-mir-6841-3p ; hsa-mir-4273

Nearest miRNA

hsa-mir-101-1/Upstream/804744; hsa-mir-1537/Downstream/78716;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/6769, chr1-CpG: 69/Downstream/17107

Upstream sequence

GGAGCAGCAGCATGATTTTTGCATATGGCATTGGAGCCATCCGCTCTTCCCCGAGAGTGGAGGTAATTTGGAACCCACACTTCCTCAATCGTACGTCCTT

Downstream sequence

ACGCATTCTCTCACGTAACAAATGGAGGGAAAGTGAGCACACATTAACTAGCGAAGCTCACAAGGCTAGATTAGGGGTGTACAGAAATCTAATTCCTGGT

Target sequence

TCAGAAGCTAAAAGGGACACTTCAGTGATCAGCAG