FMN2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016213
Fusion event
HBV-FMN2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2963
End
2998
Orient
+
Integrated sequence
GACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGA
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
240396843/240233543 (Hg38)
End
240396878/240233578 (Hg38)
Orient
+
Location type
Intronic
Target gene
FMN2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-4738-3p ; hsa-mir-374c-3p ; hsa-mir-4282
Nearest miRNA
hsa-mir-101-1/Upstream/2762352; hsa-mir-3123/Downstream/898694;
Nearest TSS
ENST00000473358/Upstream/53899; ENST00000441342/Downstream/2193;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/25317, chr1-CpG: 26/Downstream/172442
Upstream sequence
tgaggcaggagaattgcttgaacccaggaggcagaggttgcagtgagccgagattgctccgctgcactccagcctgggtgacaagagtgaaactccatct
Downstream sequence
ATTTGAAAGATGTTGCTTATTCTGAAAAACTCAATATATAAATCTTACAAAGAATAGGACCACCTCATTAATTAATTAGTAGGACCTTACAAAGAATAGG
Target sequence
TGAAGACTCATGCTGAGTTTAAGAGAAAAATTCAC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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