Basic Information
VIS ID
TVIS10016215
Fusion event
HBV-CCNYL2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2342
End
2377
Orient
+
Integrated sequence
TGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAG
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42956420/42460972 (Hg38)
End
42956455/42461007 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
CCNYL2
Nearest miRNA
hsa-mir-1265/Upstream/6819720; hsa-mir-107/Downstream/536556;
Nearest TSS
ENST00000439456/Upstream/275633; ENST00000429940/Downstream/14536;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/93204, chr10-CpG: 50/Downstream/14740
Upstream sequence
TTTACACACATATTTTTTACCTTTGCTTATTATCCTCTGGAATCTAGAGTTTTtatagcatgttggataaagagaaacagctttgatattactttgctta
Downstream sequence
GTATGATTCCATCGGAAGAAGCAAATACTGAGTTGAACAAGCTCACTCATGTCTGCTTACACCAGTCACTTTTGAATGCTCAATGGCAGGCAGGGGGAAT
Target sequence
AGGACTCCAACAAGGCACAATGACCTAGATCCTGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate