VISDB Viral Integration Site DataBase

VIS ID

TVIS10016223

Fusion event

HBV-PRMT3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1375

End

1618

Orient

-

Integrated sequence

ATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCA

Chromosome

chr11

Cytoband

p15.1

Reference genome

Start

End

20486326/20464780 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA11C ; FRA11I

Target gene

miRNAs that regulate target gene

hsa-mir-361-3p ; hsa-mir-106b-5p ; hsa-mir-1260b ; hsa-mir-5591-3p ; hsa-mir-5698 ; hsa-mir-891a-3p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-564 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-5693 ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-5704 ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-4495 ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p

Nearest miRNA

hsa-mir-210/Upstream/704450; hsa-let-7a-2/Downstream/2954325;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/76298, chr11-CpG: 123/Downstream/131871

Nearby gene

HTATIP2(-80997) ; SLC6A5(+134619) ;

Upstream sequence

ggtacacttttctctattagtccctctaaatacaaccacaatctctggacatggcatataaaagaaacagaaagaatgtaaatagtgaagagaagaagcc

Downstream sequence

ATAGAGTCTTCATTATTTCCTATCACGTGGTTAGTCAAGAGCACTCAACTTTATCTTCAAAGACCAAAGTTCATACCCTATTCCTCCCTTTAACTCTTTA

Target sequence

ATCCATGTGCACGGTAAGCTATTTCATTCTGCTTTTACAAATTTCACTAGCAGTGCAGTTGATTGGCAGGCTAATGAGTTTAATTACCAGGCTTGTGACAAATGAAAATGACTATTGCCTCTGACAGTCTACCATTGCCTTTGCTAGGCCATTGAACAGATCTGGTTAATAGGTCAGTAAACTTCAAAAAAGTTTAATTCAGTAGAAAAAGTATTAGGAAACCCTGTTTACATAATGATTTTTCTTT