VISDB Viral Integration Site DataBase

VIS ID

TVIS10016224

Fusion event

HBV-PRMT3 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1790

End

1811

Orient

-

Integrated sequence

ATAAATTGGTCTGCGCACCAGC

Chromosome

chr11

Cytoband

p15.1

Reference genome

Start

End

20486372/20464826 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA11C ; FRA11I

Target gene

miRNAs that regulate target gene

hsa-mir-361-3p ; hsa-mir-106b-5p ; hsa-mir-1260b ; hsa-mir-5591-3p ; hsa-mir-5698 ; hsa-mir-891a-3p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-564 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-5693 ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-5704 ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-4495 ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p

Nearest miRNA

hsa-mir-210/Upstream/704545; hsa-let-7a-2/Downstream/2954279;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/76393, chr11-CpG: 123/Downstream/131825

Upstream sequence

CAACATTTAGCTCTGGTTTCTTTTGAATAATTTCATTAGAAGAAACTTGTATACATTGGTCTATGATTTCACGATCttcttttttttttttttttgagac

Downstream sequence

AACTTTATCTTCAAAGACCAAAGTTCATACCCTATTCCTCCCTTTAACTCTTTACATTTAATTTAGATGGAAGATATGTTTATTTGGTAGAATATTTTAT

Target sequence

TGACAAATGAAAATGACTATTGCCTCTGACAGTCTACCATTGCCTTTGCTAGGCCATTGAACAGATCTGGTTAATAGGTCAGTAAACTTCAAAAAAGTTTAATTCAGTAGAAAAAGTATTAGGAAACCCTGTTTACATAATGATTTTTCTTTATAGAGTCTTCATTATTTCCTATCACGTGGTTAGTCAAGAGCACTC