Basic Information
VIS ID
TVIS10016225
Fusion event
HBV-chr11 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1806
End
1827
Orient
+
Integrated sequence
ACCAGCACCATGCAACTTTTTC
Host Sequence
Chromosome
chr11
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
24313926/24292380 (Hg38)
End
24314170/24292624 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-210/Upstream/873190; hsa-let-7a-2/Downstream/3222346;
Nearest TSS
ENST00000527297/Upstream/30162; ENST00000449567/Downstream/204346;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/561565, chr11-CpG: 57/Downstream/204054
Upstream sequence
ttccagccaagataggataacagaacttgaatttacctttccacctaaaacaataacaattttcatatgttgaacatcaggatatgcagaaagaactatg
Downstream sequence
ttcacaggtggaaagagtgttcattttatttcctaactcagtggtaatctcaaccttttttgtggctttgattgtcatctatatactgattgctcataaa
Target sequence
TAGATAATTTATGAATGAATTTCTCATCTGCATTGTGGGTCAAAATGATTTGGGAATTTAGAATTTCATTCACTTTTGTCTCCTCTGGCACAATATTGAGATTCATTTTTTTAACCCAAAATTTCATCCATTAAACATTTAAATATACTCAAATCTCTACTAAATTAAATGTACCCTGTATATAGGCAAATGCAGGCACACAAAGCtttctcttgaatctggtttctgctcgatctctctcttt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate