Basic Information
VIS ID
TVIS10016226
Fusion event
HBV-chr11 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1490
End
1651
Orient
-
Integrated sequence
CCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCT
Host Sequence
Chromosome
chr11
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
24313982/24292436 (Hg38)
End
24314033/24292487 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-210/Upstream/873246; hsa-let-7a-2/Downstream/3222483;
Nearest TSS
ENST00000527297/Upstream/30218; ENST00000449567/Downstream/204483;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/561621, chr11-CpG: 57/Downstream/204191
Nearby gene
CCDC179(-1432010) ; LUZP2(+204573) ;
Upstream sequence
ATAAATAACTAGTCCTTAGGGattcagtcattcggcaaatatttactgagcaagatactagatacattagtcacaggttcgattctaagaggctcattgt
Downstream sequence
TTTTTAACCCAAAATTTCATCCATTAAACATTTAAATATACTCAAATCTCTACTAAATTAAATGTACCCTGTATATAGGCAAATGCAGGCACACAAAGCt
Target sequence
TTTAGAATTTCATTCACTTTTGTCTCCTCTGGCACAATATTGAGATTCATT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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