DCDC1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016227
Fusion event
HBV-DCDC1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2304
End
2339
Orient
-
Integrated sequence
CCAAATGCCCCTATCCTATCAACACTTCCGGAGACT
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
31358116/31336569 (Hg38)
End
31358151/31336604 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
DCDC1
Nearest miRNA
hsa-mir-210/Upstream/2859021; hsa-let-7a-2/Downstream/3605233;
Nearest TSS
ENST00000527297/Upstream/8289; ENST00000527601/Downstream/33170;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/749988, chr11-CpG: 37/Downstream/32936
Upstream sequence
GGGCACAAGGGCCAGCTGTGGCTGCTGGTGAGTGTTCCCTGTGTGCCAGGTGCTGACATGCACGAGTGTGATGGTGGCCTTGCATTCCTCTTTCATCCTG
Downstream sequence
TGTCCATATGTTAGTATTTTCTAATAATTGCATAAACTTtgtggcagagactgccaattgtctgccaatatccattccttgttccttctacaaaactaga
Target sequence
ATGCATTGAAATAATTGTATTGCAATGTCCTAATG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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