Basic Information
VIS ID
TVIS10016231
Fusion event
HBV-chr11 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1779
End
1807
Orient
+
Integrated sequence
AGGCTGTAGGCATAAATTGGTCTGCGCAC
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
65478438/65710967 (Hg38)
End
65478597/65711126 (Hg38)
Orient
-
Fragile sites / regions
FRA11H
Nearest miRNA
hsa-mir-10392/Upstream/61714; hsa-let-7a-2/Downstream/1223308;
Nearest TSS
ENST00000527297/Upstream/47873; ENST00000532042/Downstream/870;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/47359, chr11-CpG: 59/Downstream/752
Nearby gene
KAT5(+1035) ;
Nearest cancer related gene
KAT5(TSG, +1035) ;
Upstream sequence
GTAAATGTCTCATTCAATGAAGAAAAATAACAGTTGAATCATAGAAATTGGAATCATTTCTGGAATAGAAACACATTATCATTGAAAGTTTGGGTAGAGC
Downstream sequence
ggtgacaccttcacagttttgaggagtattcatggggtattttgtaaaatgtttctcaattgggatttgtctgatgtttttctcatgattagactggagG
Target sequence
gacagggtttcaccgtgttggccaggatggtctcaatctcctgacctcgtgatccgcccgcctcggcctcccaaagtgctgggattataggcgtgagccaccgcgcccagccgttttgtcccattattttagatgccaagaacctgtacaccctccacc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate