Fusion event
HBV-GDPD4 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT
End
76946321/77235276 (Hg38)
Nearest miRNA
hsa-mir-10392/Upstream/1900055; hsa-let-7a-2/Downstream/2166746;
Upstream sequence
ACCCCAAGACAAAAAGTAGCAAttttctcccagagtccacacagagctggctcatgtaagctgctttcggtaagactaaacggggcctcttcagtgaggc
Downstream sequence
atagatctgtaagtttgatgcagcaaggtttttttgtacaattagcaagtggattataagattcatatggaaaagcacagccctacaataattaaaacaa
Target sequence
aattcaatgtagtaaagatgtcagttctccctcaa
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.