Basic Information
VIS ID
TVIS10016235
Fusion event
HBV-chr11 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1628
End
1663
Orient
-
Integrated sequence
CCCACCAAATATTGCCCAAGGTCTTACATAAGAGGA
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
104641656/104770929 (Hg38)
End
104641691/104770964 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10392/Upstream/920949; hsa-let-7a-2/Downstream/6576793;
Nearest TSS
ENST00000527297/Upstream/161608; ENST00000527177/Downstream/176228;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/606599, chr11-CpG: 31/Downstream/839435
Nearby gene
PDGFD(-606664) ; CASP12(+114753) ;
Upstream sequence
gatcacctggaggaattgtgttatagttgcaacaagccaacatacacctattggattagaatccctagggggagggagctggaatctgcatgttaagaaC
Downstream sequence
AAACCCAGGACTATAAATCAAATTCTTTGTTGCTCTTCCTGGATCATTTTTGCttttttttttttttttttttttttgtgagacagagtcttgctctgtt
Target sequence
TCATAAAATAGCTTGTACTATTTTACTGGGAAATT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate