Basic Information
VIS ID
TVIS10016237
Fusion event
HBV-chr11 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1703
End
1738
Orient
-
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGG
Host Sequence
Chromosome
chr11
Cytoband
q25
Reference genome
GRCh37/hg19
Start
133774761/133904866 (Hg38)
End
133774796/133904901 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7a-2/Upstream/6285;
Nearest TSS
ENST00000527297/Upstream/59328; ENST00000532272/Downstream/7217;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/39597, chr11-CpG: 29/Downstream/13436
Nearby gene
MIR4697(-3126) ; IGSF9B(+3698) ;
Upstream sequence
ccgggttcacgccactctcctgcctctgcctcccgagtagctgggactacaggcgcctgccaccacgcccagctaattttttgtatttatttttagtaga
Downstream sequence
CCTCTCCCTAAAGCAACACACACAGCCACATGGGGCTCTACACACTGCCTACTAGATCCACTTTATATGAAGAAGATACCCAGGCAGGGCTGGGTTAGAA
Target sequence
CAATCTAGAGCTGGCCAATAAGGCACCTCTTTGGC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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