Basic Information
VIS ID
TVIS10016240
Fusion event
HBV-chr12 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1774
End
1795
Orient
-
Integrated sequence
CTAGGAGGCTGTAGGCATAAAT
Host Sequence
Chromosome
chr12
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
22190144/22037210 (Hg38)
End
22190205/22037271 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1244-3/Upstream/4363816; hsa-let-7i/Downstream/2175150;
Nearest TSS
ENST00000382841/Upstream/94681; ENST00000538498/Downstream/8903;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/94787, chr12-CpG: 43/Downstream/8857
Nearby gene
CMAS(+8964) ;
Upstream sequence
atatttattaCACATACACAAATTACTACCAGTCTTATCAATTATACATATTGCCTTGGAGAAAAATGTTGCATTACAACCAATGATGAAGCACGGTATC
Downstream sequence
CATTTTTGATTGGTCATTTAGAGAACAAAGTAAAATTCTCTATTTTTCCCATTTCCTGGACTTTCTAATGATTTCAGATCAATTTTATGGATACTTGTCA
Target sequence
TCAAACATTATTAGTATTTCAAAATATTATTCTACTACAATATTTTTACTTGTTTCCATTT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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