Basic Information
VIS ID
TVIS10016241
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1388
End
1423
Orient
-
Integrated sequence
TGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTT
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
77594049/77200269 (Hg38)
End
77594084/77200304 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7i/Upstream/7615446; hsa-mir-1178/Downstream/2218953;
Nearest TSS
ENST00000382841/Upstream/134689; ENST00000552736/Downstream/28389;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/134107, chr12-CpG: 38/Downstream/1603980
Upstream sequence
ttaaggatttgattatgtataaccaaacaaataaacaaaacaattcacaaatgaacttcctggccagatggttttatcagtaagttctattaaactttca
Downstream sequence
gtccatagaggagctcctgtgagtgggtgcaaattctctttgtgtttgtgatccccaaggtttctattctctcaaattaggtaacacttggcttttagca
Target sequence
TTAGTtgccccacatctctcttgttagtaagtaag
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate