Basic Information
VIS ID
TVIS10016244
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1506
Orient
-
Integrated sequence
CTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGC| |CGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGT
Host Sequence
Chromosome
chr12
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
91086008/90692231 (Hg38)
End
91086008/90692231 (Hg38)
Orient
-
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/3947082; hsa-mir-1178/Downstream/3869558;
Nearest TSS
ENST00000382841/Upstream/69409; ENST00000549669/Downstream/117045;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/981943, chr12-CpG: 30/Downstream/261796
Nearby gene
ATP2B1-AS1(-980279) ; CCER1(+259983) ;
Upstream sequence
GCAGGTGCTATTGCAACGAGGATCTATGTATATATGTAAGATCTGGTCAGAGATGCAAGGTTTCTCAAAAGGTATAGCTCCAAGGCTTtttgtttgtttg
Downstream sequence
ctgtgaacaaacaattgaggtaactgactaccttcagacgagGCTGGAAGtttttatttatttagtgaccgacttttggtcttgtttcccaggttggagt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate