Basic Information
VIS ID
TVIS10016246
Fusion event
HBV-LOC102723490 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1807
End
1826
Orient
+
Integrated sequence
CCAGCACCATGCAACTTTTT
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
37303024/36728887 (Hg38)
End
37303133/36728996 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102723490
Nearest miRNA
hsa-mir-2276/Upstream/12566383; hsa-mir-1267/Downstream/2935038;
Nearest TSS
ENST00000623511/Upstream/54975; ENST00000472888/Downstream/90228;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/54561, chr13-CpG: 88/Downstream/90080
Upstream sequence
TGTAAATGACTAAAGGAGGGTTTCATTATCATAAACGTCTCAGACTACCTGTAGGGCTTGGAATGCAGGCAGATCTGGTTTCAAGTATCTTCTTACCTTT
Downstream sequence
TAAAATAACACTGCAATCCTCATGCATGAAATTGATGTCTGTGATTTGGTTTACAAGATTTTAATCTGCATAAAATTTTTCAGGACCACTTCTACTGCTT
Target sequence
TAAAATGTTTGTTTATAACTAAAATAGTTTGGATGCCGCTTAGCTAAAAAGATTTATTCAGCAAAAGAAAATAAAAGGCAAATAATTAAAGAGCAGAAAAACATTAAGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate