Fusion event
HBV-CAB39L integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
GTCTGCGCACCAGCACCATGCAA
End
50003928/49429792 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-2276/Upstream/5233507; hsa-mir-1267/Downstream/566623;
Upstream sequence
cttacttagtttattttattaggaaaaaataccacaaattggctgactgggtcaaaacatacatacattttttagaaccttgctatatgctgatttctaa
Downstream sequence
gggattgaacactcctttttgtgtttttcactttgttcttatgagaactataaattcatatctGTATTTCATTTACTATAGTCTTGAGATTTTTCTTATA
Target sequence
caagtacctcgttgaattcttgcttatttagaatgaaataaaatgttctcttatagttttaatttgcatttatttgattacttgt
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.