VISDB Viral Integration Site DataBase

VIS ID

TVIS10016249

Fusion event

HBV-CAB39L integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1777

Orient

-

Integrated sequence

AGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTA| |GGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAA

Chromosome

chr13

Cytoband

q14.2

Reference genome

Start

End

50004013/49429877 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-10a-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p

Nearest miRNA

hsa-mir-2276/Upstream/5233677; hsa-mir-1267/Downstream/566538;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/181310, chr13-CpG: 57/Downstream/14108

Nearby gene

CAB39L(-28278) ; SETDB2(+14415) ;

Upstream sequence

gctatatgctgatttctaaaagcaatttaatatagtttagttaactaaagatgctaccagcatgagtataccatgaggttcaccaaaacctcaccatccc

Downstream sequence

AAAAGACAATTATCTTCGGCATTTCTGGAGAGAAAAAGAATACTACAATGTTTCTTGGCAACGATCCTCACGTATTTAAGTAGCTGGATCCTCAAAATGC