VISDB Viral Integration Site DataBase

VIS ID

TVIS10016252

Fusion event

HBV-EBPL integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

3014

Orient

+

Integrated sequence

CTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGT| |TTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCC

Chromosome

chr13

Cytoband

q14.2

Reference genome

Start

End

50263403/49689267 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-132-3p ; hsa-mir-2355-5p ; hsa-mir-7106-3p ; hsa-mir-4691-3p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-2276/Upstream/5493067; hsa-mir-1267/Downstream/307148;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/103297, chr13-CpG: 63/Downstream/1821

Nearby gene

ARL11(-55395) ; KPNA3(+10039) ;

Upstream sequence

CTCAACTGCTTAATTCAAGTGCTCTCCCCACTGATCTCTGAgacacatgtacaaagacgttggtagatgcattgtttgtaatgacagaaaaatgTGTCCA

Downstream sequence

GAGATTTTTCTTATAAAATTTAATAAGTTATTTCTCATAAACATGCTTTGTTATTTGGTTCAAATATTTCTTCTAATGTTACCTTTTTTATTTTGGTTTA